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doi: 10.1016/j.phymed.2022.154494

In laboratory settings, researchers examine how Tesofensine increases the availability of key neurotransmitters in the brain, leading to enhanced satiety signaling, increased energy expenditure, and modulation of reward pathways

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However, research suggests that maintaining adequate B12 levels may help with weight management by improving energy levels[2] and overall metabolic efficiency[1], particularly for those with a deficiency

Chin Med J 2024;137:749751